Translational Sciences Research Associate (6-month contract role)
Company: PharmaEssentia U.
Location: Bedford
Posted on: April 5, 2026
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Job Description:
Translational Sciences Research Associate (6-month contract
role) Position Summary We are seeking a highly motivated Research
Associate on a 6-month contract basis to join the Translational
Sciences Department at PIRC . The candidate will be part of a
collaborative and fast-paced team driving translational research
focused on identifying novel biomarkers and exploring the
mechanism-of-action of candidate immuno-oncology and hematology
drug candidates. The role offers the opportunity to work with
samples from pharmacodynamic/pharmacokinetic and disease efficacy
mouse models and primary cells and tissues from healthy volunteers
and cancer patients. These in vitro and in vivo translational
pharmacology activities will contribute to late discovery data
packages and enable key program milestones. A strong candidate will
have a background in cancer biology , immuno-oncology , immunology,
cell biology and/or molecular biology , with prior hands-on
experience in RNA isolation and measurement, cDNA synthesis,
quantitative PCR, cell-based assays, tissue culture, and/or ELISA,
Luminex or MSD protein detection methods. The ability to work
effectively within multidisciplinary teams, follow complex
protocols, and deliver high-quality experimental data is essential.
This is an excellent opportunity to gain experience in
oncology/hematology late discovery/translational methods while
supporting impactful, real-world research. This is a 6 month
contract with potential to transition to a full-time permanent role
based on performance and project success. Upon conversion, the
employee will be eligible for our full benefits package Main
Responsibilities Isolation and quantitation of nucleic acids or
proteins from primary murine or human cell or tissue samples.
Ensure proper samples storage and maintain sample inventory for TS
department. cDNA synthesis, quantitative PCR, and building
RNAsequencing libraries. Perform in vitro and ex vivo experiments
focused on tumor-immune interactions using primary human
cell/tissue models. Culture murine and human cell lines for
cell-based assays or syngeneic tumor models. Maintain cell line
inventory for TS department. Process primary mouse or human
tumor/tissue samples for immediate downstream applications and/or
cryo-preserve and properly store for future use. Maintain sample
inventory for TS department. Detect proteins of interest in samples
from human or mouse cell lines or tissues, plasma or supernatants
using Western blotting, ELISA, Luminex or MSD. Analyze and
interpret experimental data and present findings to the team.
Maintain detailed, timely, and compliant documentation using an
electronic lab notebook (ELN). Follow lab safety and quality
standards. Basic Qualifications Bachelor’s or Master’s degree in
Cancer Biology , Immuno-oncology , Immunology , Cell Biology ,
Biomedical Sciences , or a related life science field with 2-3
years of industrial experience. Available to work full-time,
on-site for 6 months without needed work authorization/sponsorship
from the company. Preferred Qualifications Previous relevant
laboratory experience is highly preferred. Skilled in aseptic
technique and culture of mouse and human cell lines, primary cells
and tissues. Experience with tumor tissue handling , 3-D culture
systems , or ex vivo tumor models. Familiarity with immunoassays ,
qPCR, RNAsequencing, flow cytometry and/or related technologies.
Experience using an electronic lab notebook for experimental
documentation. Excellent communication, time management, and
organizational abilities. Collaborative, flexible, and motivated to
work in a fast-paced translational research environment. EEO
Statement: At PharmaEssentia Innovation Research Center (PIRC), we
are committed to providing an environment of mutual respect where
equal employment opportunities are available to all applicants
without regard to race, color, religion, sex, pregnancy (including
childbirth and related medical conditions), national origin, age,
physical and mental disability, marital status, sexual orientation,
gender identity, gender expression, genetic information (including
characteristics and testing), military and veteran status, and any
other characteristic protected by applicable law. PIRC believes
that diversity and inclusion among our team are critical to our
success as a global company, and we seek to recruit, develop and
retain the most talented people from a diverse candidate pool. PIRC
does not accept unsolicited agency resumes. Staffing agencies
should not send resumes to our HR team or to any PIRC employees.
PIRC is not responsible for any fees related to unsolicited resumes
from staffing agencies. At PharmaEssentia, our goal is to treat as
many people with cancer as possible. That means challenging the
status quo with better science that leads to better lives. By
joining our team, you will not only expand your own possibilities,
but you will contribute to expanding options for people with
cancer. https://us.pharmaessentia.com/careers/
Keywords: PharmaEssentia U., Salem , Translational Sciences Research Associate (6-month contract role), Science, Research & Development , Bedford, Massachusetts